Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions
Abstract Once materials come into contact with a biological fluid containing proteins, proteins are generally—whether desired or not—attracted by the material’s surface and adsorb onto it. The aim of this Review is to give an overview of the most commonly used characterization methods employed to gain a better understanding of the adsorption processes on either planar or curved surfaces. We continue to illustrate the benefit of combining different methods to different surface geometries of the material. The thus obtained insight ideally paves the way for engineering functional materials that interact with proteins in a predetermined manner.
An overview of the most commonly used characterization methods employed to gain a better understanding of the adsorption processes on either planar or curved surfaces is given.
@article{Morsbach_2018, title={Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions}, volume={57}, ISSN={1521-3773}, url={http://dx.doi.org/10.1002/anie.201712448}, DOI={10.1002/anie.201712448}, number={39}, journal={Angewandte Chemie International Edition}, publisher={Wiley}, author={Morsbach, Svenja and Gonella, Grazia and Mailänder, Volker and Wegner, Seraphine and Wu, Si and Weidner, Tobias and Berger, Rüdiger and Koynov, Kaloian and Vollmer, Doris and Encinas, Noemí and Kuan, Seah Ling and Bereau, Tristan and Kremer, Kurt and Weil, Tanja and Bonn, Mischa and Butt, Hans‐Jürgen and Landfester, Katharina}, year={2018}, month=aug, pages={12626–12648} }
